Detalhe da pesquisa
1.
Enhanced rare-earth separation with a metal-sensitive lanmodulin dimer.
Nature
; 618(7963): 87-93, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37259003
2.
Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis.
Nature
; 602(7896): 343-348, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35110734
3.
Discovery, structure and mechanism of a tetraether lipid synthase.
Nature
; 609(7925): 197-203, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35882349
4.
An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin.
Nature
; 566(7742): 94-99, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30728519
5.
Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N-nitrosourea-producing enzyme SznF.
Proc Natl Acad Sci U S A
; 118(4)2021 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33468680
6.
Synergistic Binding of the Halide and Cationic Prime Substrate of l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States.
Biochemistry
; 62(16): 2480-2491, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37542461
7.
Substrate-Triggered µ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate.
Biochemistry
; 61(8): 689-702, 2022 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35380785
8.
The periodic table of ribonucleotide reductases.
J Biol Chem
; 297(4): 101137, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34461093
9.
Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity.
J Biol Chem
; 296: 100693, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33894201
10.
An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme.
J Am Chem Soc
; 143(5): 2293-2303, 2021 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33522811
11.
An endogenous dAMP ligand in Bacillus subtilis class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP.
Proc Natl Acad Sci U S A
; 115(20): E4594-E4603, 2018 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29712847
12.
Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc Natl Acad Sci U S A
; 115(40): 10022-10027, 2018 10 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30224458
13.
A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF.
J Am Chem Soc
; 142(27): 11818-11828, 2020 07 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32511919
14.
Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.
Nat Methods
; 14(4): 443-449, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28250468
15.
Structure of a Ferryl Mimic in the Archetypal Iron(II)- and 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD.
Biochemistry
; 58(41): 4218-4223, 2019 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31503454
16.
A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases.
Biochemistry
; 58(12): 1627-1647, 2019 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30789718
17.
Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis.
Biochemistry
; 58(14): 1845-1860, 2019 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30855138
18.
Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical S-Adenosylmethionine Enzymes Reveals an Iron-Binding Accessory Domain in a Clostridial Enzyme.
Biochemistry
; 58(29): 3169-3184, 2019 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-31246421
19.
Steric Enforcement of cis-Epoxide Formation in the Radical C-O-Coupling Reaction by Which (S)-2-Hydroxypropylphosphonate Epoxidase (HppE) Produces Fosfomycin.
J Am Chem Soc
; 141(51): 20397-20406, 2019 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31769979
20.
Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1).
J Am Chem Soc
; 141(25): 9964-9979, 2019 06 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31117657